Article
Melanized and non-melanized multicellular form mutants of Wangiella dermatitidis in mice: mortality and histopathology studies.
Mycoses - 1 Jan 2000
Dixon D M, Migliozzi J, Cooper C R, Solis O, Breslin B, Szaniszlo P J
Abstract excerpt
One melanized (Mc3) and one non-melanized (Mc3W) multicellular form mutant of W. dermatitidis were compared with parental wild type in NYLAR mice. Each mutant grows as multicellular (muriform-like) forms in vitro at 37 degrees C and as yeasts at less than or equal to 30 degrees C. Yeast cells of all three strains were injected intravenously at concentrations of 1 x 10(4), 1 x 10(6), 1 x 10(7), 3 x 10(7) and 1 x...
Topics
- Animals
- Exophiala
- Female
- Melanins
- Mice
- Mutation
- Mycoses
- Virulence