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Article

Melanin in a meristematic mutant of Fonsecaea monophora inhibits the production of nitric oxide and Th1 cytokines of murine macrophages.

Mycopathologia - 1 Jun 2013

Zhang Junmin, Wang Li, Xi Liyan, Huang Huaiqiu, Hu Yongxuan, Li Xiqing, Huang Xiao, Lu Sha, Sun Jiufeng

Abstract excerpt

Melanin is a complex polymer which is secreted outside or constitutes the structure of fungal cell wall. It is considered as an important virulence factor in opportunistic pathogenic fungi. In this study, one albino mutant (CBS 125149) was generated from a parent meristematic mutant (CBS 122845) of Fonsecaea monophora. Transmission electron microscopy profiles showed that melanin in the parent strains appeared as...

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PMID: 23054330
DOI: 10.1007/s11046-012-9588-x

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CBS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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