Article
Molecular genetic studies of the model dematiaceous pathogen Wangiella dermatitidis.
International journal of medical microbiology : IJMM - 1 Oct 2002
Szaniszlo Paul J
Abstract excerpt
The rapidly improving molecular genetic tractability of Wangiella (Exophiala) dermatitidis significantly enhances its usefulness as a model for the more than 100 other dematiaceous (melanized) agents of human disease. Previously this model was based almost exclusively on its vegetative polymorphism, which at the simplest level is expressed as three well-characterized modes of growth (e.g., blastic, apical and...
Topics
- Cell Wall
- Chitin Synthase
- Exophiala
- Gene Expression Regulation, Fungal
- Humans
- Hyphae
- Mutation
- Virulence
- cdc42 GTP-Binding Protein
