Article
Contributions of Spore Secondary Metabolites to UV-C Protection and Virulence Vary in Different Aspergillus fumigatus Strains.
mBio - 18 Feb 2020
Blachowicz Adriana, Raffa Nicholas, Bok Jin Woo, Choera Tsokyi, Knox Benjamin, Lim Fang Yun, Huttenlocher Anna, Wang Clay C C, Venkateswaran Kasthuri, Keller Nancy P
Abstract excerpt
Fungi are versatile organisms which thrive in hostile environments, including the International Space Station (ISS). Several isolates of the human pathogen Aspergillus fumigatus have been found contaminating the ISS, an environment with increased exposure to UV radiation. Secondary metabolites (SMs) in spores, such as melanins, have been shown to protect spores from UV radiation in other fungi. To test the...
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