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Article

Conidiation color mutants of Aspergillus fumigatus are highly pathogenic to the heterologous insect host Galleria mellonella.

PloS one - 1 Jan 2009

Jackson Jennifer C, Higgins Laura A, Lin Xiaorong

Abstract excerpt

The greater wax moth Galleria mellonella has been widely used as a heterologous host for a number of fungal pathogens including Candida albicans and Cryptococcus neoformans. A positive correlation in pathogenicity of these yeasts in this insect model and animal models has been observed. However, very few studies have evaluated the possibility of applying this heterologous insect model to investigate virulence...

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PMID: 19156203
DOI: 10.1371/journal.pone.0004224
PMCID: PMC2625396

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