Article
Tyrosine O-sulfation promotes proteolytic processing of progastrin.
The EMBO journal - 3 Jul 1995
Bundgaard J R, Vuust J, Rehfeld J F
Abstract excerpt
Tyrosine O-sulfation is a common post-translational modification of secretory and membrane proteins. The biological function of sulfation is known in only a few proteins, where it appears to enhance protein-protein interactions. Based on known sequences around sulfated tyrosines, a consensus sequence for prediction of target tyrosines has been proposed. However, some proteins are tyrosine sulfated at sites that...
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