Tyrosine O-sulfation promotes proteolytic processing of progastrin.

doi:10.1002/j.1460-2075.1995.tb07310.x

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Article

Tyrosine O-sulfation promotes proteolytic processing of progastrin.

The EMBO journal - 3 Jul 1995

Bundgaard J R, Vuust J, Rehfeld J F

Abstract excerpt

Tyrosine O-sulfation is a common post-translational modification of secretory and membrane proteins. The biological function of sulfation is known in only a few proteins, where it appears to enhance protein-protein interactions. Based on known sequences around sulfated tyrosines, a consensus sequ...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cells, Cultured
Cricetinae
Gastrins
Humans
Lysine
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Protein Precursors
Protein Processing, Post-Translational
Tyrosine

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