Article
Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. I. Isolation of antibiotic-blocked mutants and their characterization.
The Journal of antibiotics - 1 Aug 1992
Yoshimoto A, Johdo O, Fujii S, Kubo K, Nishida H, Okamoto R, Takeuchi T
Abstract excerpt
Biosynthetically blocked mutants were obtained from a baumycin-producing Streptomyces sp. D788 newly isolated from soil. The first mutant isolated was a baumycin-negative but daunorubicin-accumulating mutant with a loss of 4'-substitution activity, from which all other blocked mutants were successively derived. These included a known 11-deoxydaunorubicin-producing mutant and several new types of mutants which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
