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Article

Biosynthesis of ganefromycin: results from blocked mutants and bioconversion experiments.

Journal of natural products - 1 Feb 1998

McDonald L A, Lotvin J A, Bailey A E, Carter G T

Abstract excerpt

The biosynthetic pathway of ganefromycin alpha (8) was investigated using blocked mutants of Streptomyces lydicus spp. tanzanius, the ganefromycin alpha producer, in conjunction with bioconversion experiments with the products of these mutants. Compounds 1-7 and 9-15, which are structurally related to ganefromycin alpha, were produced by cultures of secretor mutants showing blockage or diminished production of 8....

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Identifiers

PMID: 9514008
DOI: 10.1021/np970408i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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