Article
Characterization of the XRN1 gene encoding a 5'-->3' exoribonuclease: sequence data and analysis of disparate protein and mRNA levels of gene-disrupted yeast cells.
Gene - 12 Oct 1992
Larimer F W, Hsu C L, Maupin M K, Stevens A
Abstract excerpt
Sequencing of the XRN1 gene of Saccharomyces cerevisiae, cloned in this laboratory as a gene encoding a 160-kDa 5'-->3' exoribonuclease (XRN1), shows that it is identical to a gene (DST2 or SEP1) encoding a DNA strand transferase and to genes involved in nuclear fusion, KEM1, and plasmid stability, RAR5. To better understand the various phenotypes associated with loss of XRN1 and the enzymatic activities...
Topics
- Exoribonucleases
- Fungal Proteins
- Mutation
- RNA, Fungal
- RNA, Messenger
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid