Article
Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.
Genes & development - 1 Oct 1992
Forrester W, Stutz F, Rosbash M, Wickens M
Abstract excerpt
A temperature-sensitive lethal mutation in Saccharomyces cerevisiae, prp20-1, causes defects in several different steps in mRNA metabolism, including mRNA 3'-end formation, transcription initiation, and mRNA transport. Previous work has demonstrated that prp20 mutants are defective in actin pre-m...
Topics
- Base Sequence
- Biological Transport
- Cell Nucleus
- Chromatin
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Guanine Nucleotide Exchange Factors
- Hot Temperature
- In Situ Hybridization
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligonucleotides
- Plasmids
- Poly A
- RNA Processing, Post-Transcriptional
- RNA, Fungal