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Article

Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis.

Molecular and cellular biology - 1 Jan 2006

Combs D Joshua, Nagel Roland J, Ares Manuel, Stevens Scott W

Abstract excerpt

The known function of the DEXH/D-box protein Prp43p is the removal of the U2, U5, and U6 snRNPs from the postsplicing lariat-intron ribonucleoprotein complex. We demonstrate that affinity-purified Prp43p-associated material includes the expected spliceosomal components; however, we also identify several preribosomal complexes that are specifically purified with Prp43p. Conditional prp43 mutant alleles confer a...

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Identifiers

PMID: 16382144
DOI: 10.1128/MCB.26.2.523-534.2006
PMCID: PMC1346896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis.PMID 16382144Read ↗

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