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Article

Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.

Genetics - 1 Sept 1992

Detloff P, White M A, Petes T D

Abstract excerpt

Heteroduplexes formed between genes on homologous chromosomes are intermediates in meiotic recombination. In the HIS4 gene of Saccharomyces cerevisiae, most mutant alleles at the 5' end of the gene have a higher rate of meiotic recombination (gene conversion) than mutant alleles at the 3' end of the gene. Such gradients are usually interpreted as indicating a higher frequency of heteroduplex formation at the high...

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PMID: 1398048
DOI: 10.1093/genetics/132.1.113
PMCID: PMC1205110

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