Article
Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.
Genetics - 1 May 1993
Porter S E, White M A, Petes T D
Abstract excerpt
In the yeast Saccharomyces cerevisiae, the binding of the Rap1 protein to a site located between the 5' end of the HIS4 gene and the 3' end of BIK1 stimulates meiotic recombination at both flanking loci. By using strains that contain mutations located in HIS4 and BIK1, we found that most recombin...
Topics
- Alleles
- Base Sequence
- Binding Sites
- Chromosome Mapping
- Crossing Over, Genetic
- DNA, Fungal
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Meiosis
- Molecular Sequence Data
- Mutation
- Nucleic Acid Heteroduplexes
- Recombination, Genetic
- Saccharomyces cerevisiae
- rap GTP-Binding Proteins