The murine Sm-D autoantigen: multiple genes, genetic polymorphism, evolutionary conservation and lack of intervening sequences in the coding region.

doi:10.1016/0896-8411(92)90143-e

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Article

The murine Sm-D autoantigen: multiple genes, genetic polymorphism, evolutionary conservation and lack of intervening sequences in the coding region.

Journal of autoimmunity - 1 Jun 1992

Mitsuda T, Eisenberg R A, Cohen P L

Abstract excerpt

Antibodies to the Sm nuclear antigen are diagnostic of systemic lupus erythematosus (SLE). MRL/Mp-lpr/lpr mice develop a similar illness, and a proportion also develop anti-Sm. To understand better anti-Sm reactivity in this murine model, we have cloned the murine Sm-D autoantigen. One cDNA clone was 517 bp long with an open reading frame of 357 nucleotides, encoding a 13.3 kDa protein of 119 amino acids. At the...

Topics

Alleles
Amino Acid Sequence
Animals
Autoantigens
Base Sequence
DNA
Genes
Glycosylation
Humans
Mice
Mice, Mutant Strains
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Weight

Nucleic Acid Hybridization

Polymerase Chain Reaction

Protein Processing, Post-Translational

Recombinant Proteins

Ribonucleoproteins, Small Nuclear

Source

Open in PubMed

Identifiers

PMID: 1388635
DOI: 10.1016/0896-8411(92)90143-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1388635-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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