Article
Molecular genetic studies in black families with sickle cell anemia and unusually high levels of fetal hemoglobin.
Hemoglobin - 1 Jan 1992
Seltzer W K, Abshire T C, Lane P A, Roloff J S, Githens J H
Abstract excerpt
Clinical, hematologic, and molecular genetic studies are reported for five families with SS patients having unusually high fetal hemoglobin (Hb F) levels (mean 28.3%, range 19-42%). Some of the individuals were symptom-free and one was not anemic. However, some were symptomatic despite a very high Hb F. Neither the Hb F level nor the F cell distribution entirely explained the variation in clinical severity....
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