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Article

Beta S haplotypes in various world populations.

Human genetics - 1 Apr 1992

Oner C, Dimovski A J, Olivieri N F, Schiliro G, Codrington J F, Fattoum S, Adekile A D, Oner R, Yüregir G T, Altay C

Abstract excerpt

We have determined the beta S haplotypes in 709 patients with sickle cell anemia, 30 with SC disease, 91 with S-beta-thalassemia, and in 322 Hb S heterozygotes from different countries. The methodology concerned the detection of mutations in the promoter sequences of the G gamma- and A gamma-globin genes through dot blot analysis of amplified DNA with 32P-labeled probes, and an analysis of isolated Hb F by...

Topics

Africa
Anemia, Sickle Cell
Asia
Base Sequence
Genetic Testing
Globins
Haplotypes
Hemoglobin SC Disease
Humans
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Promoter Regions, Genetic

Sickle Cell Trait

Thalassemia

United States

Source

Identifiers

PMID: 1577473
DOI: 10.1007/BF00207052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1577473-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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