Potentiation of sodium chromate(VI)-induced chromosomal aberrations and mutation by vitamin B2 in Chinese hamster V79 cells.

doi:10.1016/0165-7992(92)90109-u

Back to search

Article

Potentiation of sodium chromate(VI)-induced chromosomal aberrations and mutation by vitamin B2 in Chinese hamster V79 cells.

Mutation research - 1 Nov 1992

Sugiyama M, Tsuzuki K, Lin X, Costa M

Abstract excerpt

The effect of vitamin B2, which is capable of reducing chromium(VI) to chromium(V), on chromosomal aberrations and mutation caused by Na2CrO4 was investigated in Chinese hamster V79 cells. Pretreatment with 200 microM vitamin B2 (riboflavin) for 24 h prior to exposure to Na2CrO4 (2.5-5 microM) re...

Topics

Animals
Cell Line
Chromates
Chromosome Aberrations
Cricetinae
Cricetulus
Drug Synergism
Hypoxanthine Phosphoribosyltransferase
Mutagenicity Tests
Mutagens
Mutation
Riboflavin
Sodium Compounds

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.