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Article

Genotoxicity of tri- and hexavalent chromium compounds in vivo and their modes of action on DNA damage in vitro.

PloS one - 1 Jan 2014

Fang Zhijia, Zhao Min, Zhen Hong, Chen Lifeng, Shi Ping, Huang Zhiwei

Abstract excerpt

Chromium occurs mostly in tri- and hexavalent states in the environment. Hexavalent chromium [Cr(VI)] compounds are extensively used in diverse industries, and trivalent chromium [Cr(III)] salts are used as micronutrients and dietary supplements. In the present work, we report that they both induce genetic mutations in yeast cells. They both also cause DNA damage in both yeast and Jurkat cells and the effect of...

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Identifiers

PMID: 25111056
DOI: 10.1371/journal.pone.0103194
PMCID: PMC4128586

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Source receipt: pubmed, retrieved 7 Sept 2026.

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