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The effects of 4CMB, 4HMB and BC on SCE, chromosome aberration and point mutation in cultured Chinese hamster ovary cells.

Mutation research - 1 Jan 2000

Phillips B J, James T E

Abstract excerpt

Cultured Chinese hamster ovary cells (CHO-KI-BH4) were treated for 2 h with 4CMB, 4HMB and BC, in the absence of any exogenous metabolic activation system. The cells were subjected to tests for survival, sister-chromatid exchange, chromosome aberration and mutation to thioguanine resistance. 4HMB had no effect in any test at concentrations up to 100 microgram/ml. 4CMB was slightly more toxic than BC. Both 4CMB...

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Source

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PMID: 7057758
DOI: 10.1016/0165-1218(82)90058-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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