Article
The effects of 4CMB, 4HMB and BC on SCE, chromosome aberration and point mutation in cultured Chinese hamster ovary cells.
Mutation research - 1 Jan 2000
Phillips B J, James T E
Abstract excerpt
Cultured Chinese hamster ovary cells (CHO-KI-BH4) were treated for 2 h with 4CMB, 4HMB and BC, in the absence of any exogenous metabolic activation system. The cells were subjected to tests for survival, sister-chromatid exchange, chromosome aberration and mutation to thioguanine resistance. 4HMB...
Topics
- Animals
- Benzyl Compounds
- Biphenyl Compounds
- Cell Line
- Chromosome Aberrations
- Cricetinae
- Cricetulus
- Crossing Over, Genetic
- Ethyl Methanesulfonate
- Female
- Mutagenicity Tests
- Mutagens
- Mutation
- Ovary
- Sister Chromatid Exchange
- Structure-Activity Relationship