Article
Modulation by Co(II) of UV-induced DNA repair, mutagenesis and sister-chromatid exchanges in mammalian cells.
Mutation research - 1 May 1991
Hartwig A, Snyder R D, Schlepegrell R, Beyersmann D
Abstract excerpt
In bacterial test systems, Co(II) has been shown to be antimutagenic in combination with several chemical and physical agents. To investigate whether such modulations also apply to mammalian cells, the effect of Co(II) on UV-induced mutagenesis, sister-chromatid exchanges as well as DNA damage an...
Topics
- Animals
- Cells, Cultured
- Chromatography, High Pressure Liquid
- Cobalt
- Cricetinae
- DNA Repair
- DNA, Single-Stranded
- Humans
- In Vitro Techniques
- Mutagenicity Tests
- Mutation
- Pyrimidine Dimers
- Radiation-Sensitizing Agents
- Sister Chromatid Exchange
- Ultraviolet Rays