Article
Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.
Cancer research - 15 Jun 1992
Gimenez-Conti I B, Bianchi A B, Fischer S M, Reiners J J, Conti C J, Slaga T J
Abstract excerpt
The sensitivity of outbred SENCAR mice and inbred SENCAR (SSIN) mice to multistage carcinogenesis was studied. Tumors were induced using either 7,12-dimethylbenz[a]anthracene or N-methyl-N'-nitro-N-nitrosoguanidine as initiators and 12-O-tetradecanoylphorbol-13-acetate or benzoyl peroxide as promoting agents. Although the number of papillomas per mouse was higher in SSIN than in outbred SENCAR mice, the number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
