Article
Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte.
Carcinogenesis - 1 Sept 2004
Woodworth Craig D, Michael Evan, Smith Laura, Vijayachandra Kinnimulki, Glick Adam, Hennings Henry, Yuspa Stuart H
Abstract excerpt
The multistage evolution of squamous skin tumors induced by chemical or viral carcinogens on mice from different genetic backgrounds has been a valuable model to define low penetrance loci that determine cancer susceptibility or resistance. Susceptibility determinants are multigenic, stage-specific, dependent on the carcinogenesis protocol, and in the case of initiating events, intrinsic properties of...
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