Article
Structural determinants of channel conductance in fetal and adult rat muscle acetylcholine receptors.
The Journal of physiology - 1 May 1996
Herlitze S, Villarroel A, Witzemann V, Koenen M, Sakmann B
Abstract excerpt
1. The structural basis of the developmentally regulated increase in endplate channel conductance in rat, where the gamma-subunit of the fetal muscle acetylcholine receptor (gamma-AChR) is replaced by the epsilon-subunit in the adult muscle receptor (epsilon-AChR), was investigated by analysing the structure of gamma- and epsilon-subunit genes and by expressing recombinant AChR channels of different molecular...
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