Article
Mycobacteria and human heat shock protein-specific cytotoxic T lymphocytes in rheumatoid synovial inflammation.
Arthritis and rheumatism - 1 Mar 1992
Li S G, Quayle A J, Shen Y, Kjeldsen-Kragh J, Oftung F, Gupta R S, Natvig J B, Førre O T
Abstract excerpt
OBJECTIVE: To study the cytotoxic capacity of mycobacteria-specific T lymphocyte lines and clones from sites of inflammation in patients with rheumatoid arthritis (RA). We also studied antigen specificity, surface phenotype, expression of T cell receptors (TCR), and HLA restriction. METHODS: Auto...
Topics
- Antibodies, Monoclonal
- Arthritis, Rheumatoid
- BCG Vaccine
- Clone Cells
- Cytotoxicity, Immunologic
- Epitopes
- Female
- HLA-D Antigens
- Heat-Shock Proteins
- Humans
- Male
- Membrane Proteins
- Middle Aged
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Synovial Fluid
- Synovial Membrane