Article
Selective expansion of human gamma delta T cells by monocytes infected with live Mycobacterium tuberculosis.
The Journal of clinical investigation - 1 Feb 1991
Havlir D V, Ellner J J, Chervenak K A, Boom W H
Abstract excerpt
Gamma delta (gamma delta) T cell receptor (TCR) expressing T cells comprise 3% of human peripheral blood lymphocytes, yet their role in the immune response remains largely unknown. There is evidence both in humans and in animal models that these cells participate in the immune response to mycobacterial antigens. In mice, exposure to mycobacterial antigens leads to the expansion of gamma delta T cells in draining...
Topics
- Antigens, Bacterial
- Flow Cytometry
- Humans
- Monocytes
- Mycobacterium tuberculosis
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocytes