Article
Stimulation of synovial fluid mononuclear cells with the human 65-kD heat shock protein or with live enterobacteria leads to preferential expansion of TCR-gamma delta+ lymphocytes.
Clinical and experimental immunology - 1 Sept 1992
Hermann E, Lohse A W, Mayet W J, van der Zee R, Van Eden W, Probst P, Poralla T, Meyer zum Büschenfelde K H, Fleischer B
Abstract excerpt
T lymphocyte responses to heterologous or self 65-kD heat shock protein (hsp) have been implicated in the pathogenesis of various forms of arthritis. To delineate the relationship of 65-kD hsp to different synovial fluid (SF) T cell subsets, we stimulated synovial fluid (SFMC) and peripheral bloo...
Topics
- Cell Line
- Clone Cells
- Enterobacteriaceae
- Heat-Shock Proteins
- Humans
- Lymphocyte Activation
- Monocytes
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta
- Synovial Fluid
- T-Lymphocytes