Article
Stimulation of synovial fluid mononuclear cells with the human 65-kD heat shock protein or with live enterobacteria leads to preferential expansion of TCR-gamma delta+ lymphocytes.
Clinical and experimental immunology - 1 Sept 1992
Hermann E, Lohse A W, Mayet W J, van der Zee R, Van Eden W, Probst P, Poralla T, Meyer zum Büschenfelde K H, Fleischer B
Abstract excerpt
T lymphocyte responses to heterologous or self 65-kD heat shock protein (hsp) have been implicated in the pathogenesis of various forms of arthritis. To delineate the relationship of 65-kD hsp to different synovial fluid (SF) T cell subsets, we stimulated synovial fluid (SFMC) and peripheral blood mononuclear cells (PBMC) from patients with different inflammatory rheumatic diseases and from healthy controls with...
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