Synovial cells responding to a 65-kDa mycobacterial heat shock protein have a high proportion of a TcR gamma delta subtype uncommon in peripheral blood.

doi:10.1111/j.1365-3083.1990.tb03191.x

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Article

Synovial cells responding to a 65-kDa mycobacterial heat shock protein have a high proportion of a TcR gamma delta subtype uncommon in peripheral blood.

Scandinavian journal of immunology - 1 Nov 1990

Söderström K, Halapi E, Nilsson E, Grönberg A, van Embden J, Klareskog L, Kiessling R

Abstract excerpt

We have analysed the ability of T cells from synovial fluid mononuclear cells (SFMC) and from peripheral blood mononuclear cells (PBMC) of inflammatory arthritic diseases to proliferate in response to mycobacterial antigens (65-kDa heat shock protein [hsp] of BCG, whole BCG) and to rat collagen type II. The SFMC demonstrated a significantly greater ability to respond to 65-kDa hsp of BCG, and to whole BCG,...

Topics

Antigens, Bacterial
Arthritis
Arthritis, Rheumatoid
Collagen
Heat-Shock Proteins
Humans
Interleukin-2
Leukocytes, Mononuclear
Lymphocyte Activation
Molecular Weight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium bovis

Phenotype

Phytohemagglutinins

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, gamma-delta

Synovial Fluid

T-Lymphocytes

Tetanus Toxoid

Source

Open in PubMed

Identifiers

PMID: 2148638
DOI: 10.1111/j.1365-3083.1990.tb03191.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2148638-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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