Molecular genetic analysis of HLA-DR and HLA-DQ genes among anti-U1-70-kd autoantibody positive connective tissue disease patients.

doi:10.1002/art.1780350113

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Article

Molecular genetic analysis of HLA-DR and HLA-DQ genes among anti-U1-70-kd autoantibody positive connective tissue disease patients.

Arthritis and rheumatism - 1 Jan 1992

Kaneoka H, Hsu K C, Takeda Y, Sharp G C, Hoffman R W

Abstract excerpt

OBJECTIVE: We have recently found that the presence of autoantibodies against the 70-kd polypeptide of U1 RNP (U1-70-kd) is associated with HLA-DR4 and DR2. To further characterize this association, we performed a molecular genetic analysis of HLA-DR and DQ genes among patients with autoantibodie...

Topics

Amino Acid Sequence
Autoantibodies
Base Sequence
Connective Tissue Diseases
DNA
Epitopes
Female
Genotype
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DRB1 Chains

HLA-DRB5 Chains

Haplotypes

Histocompatibility Antigens Class II

Humans

Male

Source

Open in PubMed

Identifiers

PMID: 1370621
DOI: 10.1002/art.1780350113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1370621-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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