Article
Association of specific amino acid sequence of HLA-DR with rheumatoid arthritis in Koreans and its diagnostic value.
The Journal of rheumatology - 1 Oct 1996
Hong G H, Park M H, Takeuchi F, Oh M D, Song Y W, Nabeta H, Nakano K, Ito K, Park K S
Abstract excerpt
OBJECTIVE: To analyze the association of susceptibility epitopes and alleles of HLA-DRB1 with rheumatoid arthritis (RA) in Koreans. METHODS: We performed HLA-DRB1 epitope typing in 61 patients and 82 controls using polymerase chain reaction (PCR) oligonucleotide hybridization, and HLA-DR4, DR1, and DR8 alleles were characterized by PCR single strand conformation polymorphism (SSCP). RESULTS: The frequency of...
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