Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune disease.

Journal of autoimmunity - 1 Jun 2006

Muro Yoshinao, Ogawa Yasushi, Sugiura Kazumitsu, Tomita Yasushi

Abstract excerpt

Autoantibodies against DFS70/LEDGF, which is also known as an important partner of HIV-1 integrase, are found in 10% of healthy Japanese people, but in only approximately 2% of patients with systemic autoimmune disease (SAD). We wished to characterize the association of HLA class II alleles with the presence of autoantibodies against this molecule. MHC class II genes (DR, DQ, and DP alleles) were analyzed by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Adaptor Proteins, Signal Transducing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoimmune Diseases

Share to Connective Tissue Diseases

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Source

Identifiers

PMID: 16713178
DOI: 10.1016/j.jaut.2006.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune disease.PMID 16713178Read ↗

Autoantibodies Against DFS70/LEDGF Exclusion Markers for Systemic Autoimmune Rheumatic Diseases (SARD)Semantic proximity Read ↗

Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain.Semantic proximity Read ↗

Molecular genetic analysis of HLA-DR and HLA-DQ genes among anti-U1-70-kd autoantibody positive connective tissue disease patients.Semantic proximity Read ↗

Anti-DFS70 Antibodies Among Patient and Healthy Population Cohorts in China: Results From a Multicenter Training Program Showing Spontaneous Abortion and Pediatric Systemic Autoimmune Rheumatic Diseases Are Common in Anti-DFS70 Positive Patients.Semantic proximity Read ↗

HLA-DRB1*04 alleles in Japanese rheumatoid arthritis patients with AA amyloidosis.Semantic proximity Read ↗

HLA-DPB1*0401 is associated with the presence of autoantibodies reactive with the U1-70 kD polypeptide antigen of U1-small nuclear ribonucleoprotein among connective tissue disease patients.Semantic proximity Read ↗

Direct sequencing of a HLA-DRB gene by polymerase chain reaction: sequence variation in DRw8 specificity.Semantic proximity Read ↗

The HLA-DR and DQ genes control the autoimmune response to DNA topoisomerase I in systemic sclerosis (scleroderma).Semantic proximity Read ↗

Demonstration of high prevalence of SS-A antibodies in a general population: association with HLA-DR and enterovirus antibodies.Semantic proximity Read ↗

Autoantibodies detectable in the sera of silicosis patients. The relationship between the anti-topoisomerase I antibody response and HLA-DQB1*0402 allele in Japanese silicosis patients.Semantic proximity Read ↗

HLA class II genes associated with anticentromere antibody in Japanese patients with systemic sclerosis (scleroderma).Semantic proximity Read ↗

Association of DQB1*0302 alloantigens in Japanese pediatric patients with steroid-sensitive nephrotic syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.