Article
beta2-adrenoceptor gene polymorphisms and blood pressure variations in East Anglian Caucasians.
Journal of hypertension - 1 Jun 2000
Jia H, Sharma P, Hopper R, Dickerson C, Lloyd D D, Brown M J
Abstract excerpt
OBJECTIVE: The amino-terminal polymorphisms, Arg16Gly and Gln27Glu, of the beta2-adrenergic receptor (beta2AR) have been shown to affect regulation of the receptor expression by an agonist in cell culture studies. The Arg16Gly polymorphism has also been recently shown to be associated with essential hypertension. We therefore evaluated whether the amino-terminal polymorphisms of beta2AR are associated with...
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