Article
Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate.
The Journal of allergy and clinical immunology - 1 Sept 2003
Wisnewski Adam V, Herrick Christina A, Liu Qing, Chen Liang, Bottomly Kim, Redlich Carrie A
Abstract excerpt
BACKGROUND: The human immune response to isocyanate, a leading cause of occupational asthma, remains incompletely characterized, including the cell types involved and the form of the chemical that acts as an antigen. OBJECTIVE: The purpose of this investigation was to characterize human T cells that respond to hexamethylene diisocyanate (HDI), an aliphatic isocyanate routinely used in the automobile body...
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