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Article

A yeast system for stable expression of hepatitis B surface antigen.

Journal of biotechnology - 1 Jun 1990

Shiosaki K, Miyatsu Y, Takahara K, Mizokami H, Hamada F, Matsubara K

Abstract excerpt

We have constructed a yeast strain that has integrated into its chromosomal ribosomal RNA gene site two copies of Hepatitis B virus surface (HBS) antigen gene under the control of the yeast (Saccharomyces cerevisiae) glyceraldehyde-3-phosphate dehydrogenase (GAP) promoter and terminator. The level of expression of HBS gene was low in the strain, but upon chemical and physical mutageneses, in combination with an...

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PMID: 1366913
DOI: 10.1016/0168-1656(90)90122-r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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