Article
Effector phenotype and immunologic specificity of T-cell-mediated adoptive therapy for a murine tumor that lacks intrinsic immunogenicity.
Cellular immunology - 1 Aug 1990
Sakai K, Chang A E, Shu S
Abstract excerpt
The MCA 102 sarcoma has been defined by a variety of immunologic studies as a tumor lacking intrinsic immunogenicity. Nevertheless, we have recently demonstrated the feasibility of generating therapeutically effective lymphocytes for adoptive immunotherapy of this tumor. Procedures to achieve thi...
Topics
- Adjuvants, Immunologic
- Animals
- Antigens, Neoplasm
- Disease Models, Animal
- Female
- Immunization
- Immunization, Passive
- Immunotherapy
- Interleukin-2
- Lymph Nodes
- Lymphocyte Depletion
- Mice
- Mice, Inbred C57BL
- Phenotype
- Propionibacterium acnes
- Sarcoma, Experimental
- T-Lymphocytes