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Article

Cytotoxicity of 125I decay in the DNA double strand break repair deficient mutant cell line, xrs-5.

International journal of radiation biology - 1 Nov 1992

Yasui L S

Abstract excerpt

The survival of parental Chinese hamster ovary (CHO) K1 cells and the DNA double strand break (DSB) repair deficient mutant, xrs-5 was determined after accumulation of 125I decays. Both CHO and xrs-5 cells were extremely sensitive to accumulated 125I decays. The D0 values for CHO and xrs-5 cells were 40 and approximately 7 decays per cell, respectively. The difference in cell survival between CHO and xrs-5 cells...

Topics

Animals
CHO Cells
Cell Survival
Cricetinae
DNA Damage
DNA Repair
Iodine Radioisotopes
Mutation
Relative Biological Effectiveness

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1361518
DOI: 10.1080/09553009214552531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1361518-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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