Article
Changes in the nuclear structure in the radiation-sensitive CHO mutant cell, xrs-5.
Radiation research - 1 Sept 1991
Yasui L S, Ling-Indeck L, Johnson-Wint B, Fink T J, Molsen D
Abstract excerpt
The structural organization of the cell nucleus was investigated by transmission electron microscopy in the radiosensitive Chinese hamster ovary (CHO) cell mutant, xrs-5 (D0 = 45 cGy), relative to parental K1 cells (D0 = 200 cGy). In 99% of all xrs-5 cells, the outer layer of the nuclear envelope was separated from the inner layer, while 96% of K1 cells had closely apposed layers. This separation of the inner and...
Topics
- Animals
- Cell Nucleus
- Cell Survival
- Cells, Cultured
- Cesium Radioisotopes
- Dose-Response Relationship, Radiation
- Gamma Rays
- Microscopy, Electron
- Mutation
- Radiation Tolerance