Article
Relationship between PCC fragments and cell killing studied in X-irradiated CHO, CHO-K1 cells and two radiosensitive mutants xrs1 and xrs5.
International journal of radiation biology - 1 Dec 1997
Borgmann K, Dikomey E
Abstract excerpt
PURPOSE: To investigate the correlation between PCC fragments and cell killing. MATERIALS AND METHODS: Induction and repair of DNA fragments were measured in CHO, CHO-K1, xrs1 and xrs5 cells using the premature chromosome condensation (PCC) technique and cell survival was determined by a colony assay. RESULTS: The number of PCC fragments measured in cells immediately fused after X-irradiation was the same for CHO...
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