Efficient mutation induction by 125I and 131I decays in DNA of human cells.

Article

Efficient mutation induction by 125I and 131I decays in DNA of human cells.

Radiation research - 1 Jul 1990

Whaley J M, Little J B

Abstract excerpt

To examine the role of radiation energy deposition in DNA on cellular effects, we investigated the ability of 125IdUrd and 131IdUrd to kill cells and induce mutations at the hprt locus. We employed human lymphoblastoid cells proficient (TK6) or deficient (SE30) in the ability to incorporate a thy...

Topics

Cell Line
Cell Survival
DNA
Humans
Idoxuridine
Iodine Radioisotopes
Mutation
Radioactivity

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