Article
Efficient mutation induction by 125I and 131I decays in DNA of human cells.
Radiation research - 1 Jul 1990
Whaley J M, Little J B
Abstract excerpt
To examine the role of radiation energy deposition in DNA on cellular effects, we investigated the ability of 125IdUrd and 131IdUrd to kill cells and induce mutations at the hprt locus. We employed human lymphoblastoid cells proficient (TK6) or deficient (SE30) in the ability to incorporate a thymidine analog into DNA by way of the thymidine kinase (TK) scavenger pathway. Iodine-125 releases a shower of...
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