Article
v-erbB oncogene expression accounts for most variations in protein synthesis after avian erythroblastosis virus infection of chicken embryo fibroblasts: a two-dimensional electrophoresis study.
Electrophoresis - 1 Jun 1992
Desbois C, Gandrillon O, Samarut J, Madjar J J
Abstract excerpt
The effect of the v-erbA and/or v-erbB oncogenes on cellular gene expression was investigated after separation by two-dimensional polyacrylamide gel electrophoresis of [35S]methionine-labelled proteins from chicken embryo fibroblasts (CEF), infected by either the avian erythroblastosis virus (AEV) carrying both oncogenes, or by viruses carrying only one of them. We observed significant changes in the synthesis of...
Topics
- Alpharetrovirus
- Animals
- Avian Leukosis
- Cell Transformation, Viral
- Cells, Cultured
- Chick Embryo
- Chromosome Deletion
- Electrophoresis, Gel, Two-Dimensional
- Fibroblasts
- Gene Expression Regulation, Viral
