Article
Investigation of the mode of inheritance of insulin-dependent diabetes mellitus in Japanese subjects.
American journal of human genetics - 1 May 1992
Jenkins D, Penny M A, Uchigata Y, Jacobs K H, Mijovic C H, Hirata Y, Otani T, Fletcher J, Bradwell A R, Barnett A H
Abstract excerpt
Previous studies have shown that insulin-dependent diabetes mellitus is positively associated with HLA-DR4 and HLA-DR9 in Japanese populations. It was proposed that susceptibility to the disease is determined by a single HLA allele associated with both DR4 and DR9. DR genotypes in a Japanese population with insulin-dependent diabetes mellitus were determined by DRB/DQB RFLP analysis. A single...
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