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Article

Investigation of the mode of inheritance of insulin-dependent diabetes mellitus in Japanese subjects.

American journal of human genetics - 1 May 1992

Jenkins D, Penny M A, Uchigata Y, Jacobs K H, Mijovic C H, Hirata Y, Otani T, Fletcher J, Bradwell A R, Barnett A H

Abstract excerpt

Previous studies have shown that insulin-dependent diabetes mellitus is positively associated with HLA-DR4 and HLA-DR9 in Japanese populations. It was proposed that susceptibility to the disease is determined by a single HLA allele associated with both DR4 and DR9. DR genotypes in a Japanese population with insulin-dependent diabetes mellitus were determined by DRB/DQB RFLP analysis. A single...

Topics

Adult
Alleles
Asian People
Diabetes Mellitus, Type 1
Disease Susceptibility
Female
Gene Frequency
HLA-DQ Antigens
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DR4 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 1349195
PMCID: PMC1682608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1349195-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Investigation of the mode of inheritance of insulin-dependent diabetes mellitus in Japanese subjects.PMID 1349195Read ↗

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