Article
Immunogenetic heterogeneity in type 1 (insulin-dependent) diabetes among Japanese--class II antigen and autoimmune thyroid disease.
Diabetes research and clinical practice - 1 Jan 1995
Chikuba N, Akazawa S, Yamaguchi Y, Kawasaki E, Takino H, Yoshimoto M, Ohe N, Yamashita K, Yano A, Nagataki S
Abstract excerpt
HLA-DQA1 and DPB1 alleles were examined in relation to autoimmune thyroid disease (AITD) in the Japanese type 1 diabetic patients. The subjects consisted of 14 type 1 diabetic patients with Graves' disease, 12 patients with Hashimoto's thyroiditis and 32 type 1 diabetic patients without AITD. Com...
Topics
- Adult
- Age of Onset
- Alleles
- Autoantibodies
- Base Sequence
- DNA Primers
- Diabetes Mellitus, Type 1
- Female
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Islets of Langerhans
- Japan
