Article
Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans.
Human immunology - 1 Dec 1998
Park Y S, Wang C Y, Ko K W, Yang S W, Park M, Yang M C, She J X
Abstract excerpt
The association of HLA-DRB1 and DQB1 genes with IDDM in Koreans was assessed using 115 IDDM patients and 140 nondiabetic controls. DQB1*0201 is the only DQB1 allele positively associated with IDDM while DQB*0602, *0601 and *0301 are negatively associated. Three DRB1 alleles (DRB1*0301, DRB1*0407 and DRB1*0901) are positively associated while four DR allele groups (DRB1*15, DRB1*12, DRB1*10 and DRB1*14) are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.