Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage analysis of insulin-receptor gene in familial NIDDM.

Diabetes - 1 May 1992

Elbein S C, Sorensen L K, Taylor M

Abstract excerpt

Although non-insulin-dependent diabetes mellitus (NIDDM) is clearly inherited, the mode of inheritance and genetic etiology remain unknown. Impaired insulin action is an important component of NIDDM, which may precede NIDDM onset, and appears to be inherited. Numerous defects of the insulin-receptor gene have been described in syndromes of extreme insulin resistance, and this gene is a strong candidate for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Haplotypes

Share to Models, Genetic

Share to Pedigree

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1348997
DOI: 10.2337/diab.41.5.648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage analysis of insulin-receptor gene in familial NIDDM.PMID 1348997Read ↗

Do non-insulin-dependent diabetes mellitus (NIDDM) and insulin-dependent diabetes mellitus (IDDM) share genetic susceptibility loci? An analysis of putative IDDM susceptibility regions in familial NIDDM.Semantic proximity Read ↗

Linkage studies in NIDDM with markers near the sulphonylurea receptor gene.Semantic proximity Read ↗

A microsatellite polymorphism in the human insulin receptor gene: a highly informative marker for linkage analysis.Semantic proximity Read ↗

Major gene effect for insulin levels in familial NIDDM pedigrees.Semantic proximity Read ↗

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.Semantic proximity Read ↗

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Genetic variation in insulin receptor beta-chain exons among members of familial type 2 (non-insulin-dependent) diabetic pedigrees.Semantic proximity Read ↗

Genetic analyses of glucose transporter genes in French non-insulin-dependent diabetic families.Semantic proximity Read ↗

Use of DNA polymorphisms for genetic analysis of non-insulin dependent diabetes mellitus.Semantic proximity Read ↗

Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair.Semantic proximity Read ↗

A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter.Semantic proximity Read ↗

Linkage analysis of glucokinase gene with NIDDM in Caucasian pedigrees.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.