Linkage analysis of insulin-receptor gene in familial NIDDM.

doi:10.2337/diab.41.5.648

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Article

Linkage analysis of insulin-receptor gene in familial NIDDM.

Diabetes - 1 May 1992

Elbein S C, Sorensen L K, Taylor M

Abstract excerpt

Although non-insulin-dependent diabetes mellitus (NIDDM) is clearly inherited, the mode of inheritance and genetic etiology remain unknown. Impaired insulin action is an important component of NIDDM, which may precede NIDDM onset, and appears to be inherited. Numerous defects of the insulin-recep...

Topics

Adult
Aged
Alleles
DNA
Diabetes Mellitus, Type 2
Female
Genetic Linkage
Genetic Testing
Glucose Tolerance Test
Haplotypes
Humans
Insulin Resistance
Male
Middle Aged
Models, Genetic
Pedigree
Polymorphism, Restriction Fragment Length

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