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Article

Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair.

The Journal of clinical endocrinology and metabolism - 1 Dec 1996

Elbein S C, Hoffman M, Barrett K, Wegner K, Miles C, Bachman K, Berkowitz D, Shuldiner A R, Leppert M F, Hasstedt S

Abstract excerpt

Obesity and insulin resistance are important risk factors for the development of noninsulin-dependent diabetes (NIDDM) and are prevalent among predisposed first degree relatives of diabetic individuals. Recent molecular screening and analysis of a common missense mutation of the beta 3-adrenergic receptor gene suggested this locus as a strong candidate for increased obesity, earlier age of diabetes onset, and...

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Source

Identifiers

PMID: 8954053
DOI: 10.1210/jcem.81.12.8954053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair.PMID 8954053Read ↗

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