Article
A microsatellite polymorphism in the human insulin receptor gene: a highly informative marker for linkage analysis.
Diabetes research and clinical practice - 1 Apr 1993
Ikegami H, Fukuda M, Kawaguchi Y, Fujioka Y, Ueda H, Ogihara T
Abstract excerpt
To study genetic susceptibility to non-insulin dependent diabetes mellitus (NIDDM), association of insulin receptor gene, a candidate gene for NIDDM, with NIDDM was studied. A microsatellite polymorphism located in intron 2 of the human insulin receptor gene was detected by the polymerase chain reaction and used as a genetic marker. Eight different alleles were observed, indicating highly polymorphic nature of...
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