Article
Polymorphisms at the GLUT1 (HepG2) and GLUT4 (muscle/adipocyte) glucose transporter genes and non-insulin-dependent diabetes mellitus (NIDDM).
Human genetics - 1 Mar 1992
Baroni M G, Oelbaum R S, Pozzilli P, Stocks J, Li S R, Fiore V, Galton D J
Abstract excerpt
In order to determine the possible contribution of the GLUT1 (HepG2) glucose transporter gene to the inheritance of non-insulin-dependent diabetes mellitus (NIDDM), two restriction fragment length polymorphisms (RFLPs) and the related haplotypes at this locus were studied in 48 Italian diabetic patients and 58 normal subjects. Genotype frequencies for the XbaI polymorphism were significantly different between...
Topics
- Adipose Tissue
- Blood Glucose
- Carcinoma, Hepatocellular
- Cell Line
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Humans
