Article
Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations.
Acta diabetologica - 1 Sept 1996
Pontiroli A E, Capra F, Veglia F, Ferrari M, Xiang K S, Bell G I, Baroni M G, Galton D J, Weaver J U, Hitman G A, Kopelman P G, Mohan V, Viswanathan M
Abstract excerpt
Polymorphic variation of genes encoding the glucose transporters glycoproteins (GLUT) may contribute to the genetic susceptibility to type 2 (non-insulin-dependent) diabetes. In this study we evaluated the allele and genotype frequencies of GLUT1 and GLUT4 restriction fragment length polymorphism (RFLP), revealed by digestion with XbaI for GLUT1 and KpnI for GLUT4, in Caucasian, Chinese, Japanese, Asian Indian...
Topics
- Adult
- Alleles
- Body Mass Index
- Chi-Square Distribution
- Confidence Intervals
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Ethnicity