Article
High frequency of polymorphism but no mutations found in the GLUT1 glucose transporter gene in NIDDM and familial obesity by SSCP analysis.
Human genetics - 1 Apr 1998
Baroni M G, D'Andrea M P, Capici F, Buzzetti R, Cavallo M G, Fallucca F, Giovannini C, Pozzilli P
Abstract excerpt
To evaluate whether a structural defect in the human glucose transporter gene GLUT1 could be involved in the aetiology of insulin resistance, a key factor of non-insulin-dependent diabetes mellitus (NIDDM) and obesity, we performed single-strand conformation polymorphism (SSCP) analysis in 40 subjects (20 NIDDM patients and 20 subjects with familial obesity). The GLUT1 gene, which is involved in basal glucose...
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