Article
Polymorphisms of GLUT2 and GLUT4 genes. Use in evaluation of genetic susceptibility to NIDDM in blacks.
Diabetes - 1 Dec 1990
Matsutani A, Koranyi L, Cox N, Permutt M A
Abstract excerpt
The liver/islet (GLUT2) and muscle/adipose tissue (GLUT4) glucose-transporter gene products, membrane proteins that facilitate glucose uptake into cells, are important molecules for normal carbohydrate metabolism. Recent isolation of the genes encoding these proteins provides a means to assess th...
Topics
- Alleles
- Autoradiography
- Black People
- Chromosome Mapping
- Cloning, Molecular
- DNA
- DNA Probes
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Evaluation Studies as Topic
- Gene Frequency
- Genetic Linkage
- Genetic Testing
- Haplotypes
- Humans
- Liver
- Middle Aged
- Monosaccharide Transport Proteins