Polymorphisms of HepG2/erythrocyte glucose-transporter gene. Linkage relationships and implications for genetic analysis of NIDDM.

doi:10.2337/diacare.39.1.49

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Article

Polymorphisms of HepG2/erythrocyte glucose-transporter gene. Linkage relationships and implications for genetic analysis of NIDDM.

Diabetes - 1 Jan 1990

Kaku K, Matsutani A, Mueckler M, Permutt M A

Abstract excerpt

To assess the contribution of the HepG2/erythrocyte glucose-transporter (HepG2 GT) gene to the inherited susceptibility to non-insulin-dependent diabetes mellitus (NIDDM), cDNA and genomic probes were used to search for restriction-endonuclease polymorphisms at this locus. Analysis of DNA from 16 unrelated Black American individuals with 19 enzymes and as many as six different probes, defined four polymorphisms...

Topics

Black People
Chromosome Mapping
DNA
DNA Restriction Enzymes
Diabetes Mellitus, Type 2
Evaluation Studies as Topic
Gene Frequency
Genetic Linkage
Genotype
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Monosaccharide Transport Proteins

Nucleotides

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Black or African American

Source

Open in PubMed

Identifiers

PMID: 1976557
DOI: 10.2337/diacare.39.1.49

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1976557-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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